Therapeutic depletion of monocyte-derived cells protects from long-term axonal loss in experimental autoimmune encephalo...
Published in Journal of Neuroimmunology
Studies in multiple sclerosis and its animal model experimental autoimmune encephalomyelitis (EAE) suggest that peripheral monocyte-derived cells (MDCs) are instrumental for disease initiation. MDCs, however, are plastic, and may exert various functions once in the central nervous system (CNS) for prolonged periods. Furthermore, the long-term effec...
