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Structure, functions, and evolution of the third complement component and viral molecular mimicry.

Sahu, A Sunyer, Jo Moore, Wt Sarrias, Mr Athena Soulika Lambris, Jd

Published in Immunologic Research

The third component of the complement system, C3, is a common denominator in the activation of the classical, alternative, and lectin pathways. The ability of C3 molecule to interact with at least 20 different proteins makes it the most versatile component of this system. Since these interactions are important for phagocytic, immunoregulatory, and ...

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